Dr. Wang ‘s ongoing research focuses on genetics and molecular cancer biology working with the human body’s immune system. She has profound experience with cell biology and xenograft mice model experience with cancer immunology and immunotherapy. She also has 10 years clinical experience with ophthalmology in China.
1, Yue Wang; Mengying Hu; Olivera J Finn; Xiaosong Wang. Tumor associated antigen burden predicts immune checkpoint blockade benefit in tumor entities with low T cell exhaustion and mutation burden. Cancer cell. Mar 2023. Accepted
2, Lee S, Deng L, Wang Yue, Wang K, Sartor MA, Wang XS#
IndepthPathway: an integrated tool for in-depth pathway enrichment analysis based on single cell sequencing data.Bioinformatics. 2023. In Press
3, Wang, XS., Lee, S., Zhang, H, Yue Wang. An integral genomic signature approach for tailored cancer therapy using genome-wide sequencing data. Nat Commun 13, 2936 (2022). https://doi.org/10.1038/s41467-022-30449-7
4. Yuan JM, Wang Y, Wang R, Luu HN, Adams-Haduch J, Koh WP, Gao YT, Behari J, Lotze MT. Serum interleukin-27 in relation to risk of hepatocellular carcinoma in two nested case-control studies. Cancer Epidemiol Biomarkers Prev. 2020 Nov 17:cebp.1081.2020. doi: 10.1158/1055-9965.EPI-20-1081. Epub ahead of print. PMID: 33203693.
5.Yue Wang, Suqin Zhang, Xingquan Zhang, Suet Kee Loo, Pranav Murthy, Carolina Gongulho, Lin Zhang, Michael Lotze. Apoptosis-resistant (PUMA-/-, p53-\-, Bax-\-) human colorectal cancer HCT116 cell lines expressing mt-Keima as a sensitive mitophagy assay. TRCCC Meeting, Seven Spring, PA, Mar 5th, 2020
6. Yue Wang, Alexa Fort, Miranda Steel, Jian Han, Herbert Zeh, Michael T Lotze. Deep Serial Analysis of the TCR/BCR CDR3 Adaptome Repertoire in periferal Blood of Pancreatic Cancer Patients in a Randomized Study of Neoadjuvant Chemotherapy with or without Autophagy Inhibition. AACR meeting, Atlanta, GA, Apr 2019
7. Yue Wang, Leonard J. Appleman, Shuyan Zhai, Partha Roy, and Michael T. Lotze. A New Damage Associated Molecular Pattern Molecule (DAMP)? Increase in Serum Profilin 1 (Pfn1) in Renal Cancer Patients Treated with High Dose Interleukin 2 (IL-2) and Hydroxychloroquine (HCQ). TRCCC Meeting, Feb 14,2019
8. Murthy P, Ekeke CN, Russell KL, Butler SC, Wang Y, Luketich JD, Soloff AC, Dhupar R, Lotze MT Making Cold malignant pleural effusions hot: driving novel immunotherapies. Oncoimmunology. 2019 Jan 22