Specialties
- Clinical Pharmacology
- Therapeutic Drug Monitoring
- Toxicology
Appointments
2019 - Present | Shankara Cancer Research Institute (Bangalore, India) | Adjunct Visiting Professor |
2010 - Present | University of Pittsburgh Magee Women’s Research Inst. | Professor |
2009 - Present | University of Pittsburgh Medical Center Department of Pathology | Director TDM, Toxicology |
2004 - Present | University of Pittsburgh Hillman Cancer Institute | Professor |
2001 - Present | University of Pittsburgh McGowern Inst. of Regenerative Medicine | Professor |
1995 | University of Pittsburgh Center for Clinical Pharmacology | Professor |
1994 - 1995 | K.J. Post Graduate Education and Research Foundation (Madras, India) | Adjunct Professor |
1991 - Present | University of Pittsburgh Department of Pathology | Professor |
1983 - Present | University of Pittsburgh Thomas Starl Transplantation Institute | Professor |
1980 - Present | University of Pittsburgh Department of Pharmacy & Therapeutics | Professor, Associate Professor, Assistant Professor |
1978 - 1980 | University of Washington School of Pharmacy | Research Associate w/ Dr. Milo Gribaldi |
1971 - 1972 | Stanley Hospital (Madras, India) | Hospital Training |
Editorial Board
- American Journal of Analytical Chemistry - current Editor
- Therapeutic Drug Monitoring – current – Editorial board member
- Frontiers in Pharmacology – current Editorial board member
- Frontiers in Pediatrics and OBGYN – current editorial board member
- Open Current Clinical Pharmacology – Current Editorial Board member
- Open Clinical and Experimental Pharmacology – editorial board member
- Open Transplantation – editorial board member
- Open-International Journal of Pharmacokinetics – editorial Board member
- BOAJ Pharmaceutical Sciences – current Invited Editorial Board member
- Invited to several additional editorial boards in 2017-2024
Optimizing drug therapy in special patient populations.
The research in his laboratory revolves around “LIFE”. One half addresses, “prevention of preterm labor—giving life for the first time” by optimizing the use of 17-hydroxyprogesterone caproate during pregnancy and personalizing buprenorphine use during pregnancy; Second half addresses “optimization of use of medications in organ transplant patients—a second chance in life” and assessing the functional capacity of transplanted organs. Consistently funded for OBGYN pharmacology work for the past 18 years.
Presented more than 250 lectures/seminars at national/international meetings.
Published over 450 papers in peer reviewed journals and contributed to book chapters.
Mentored: 45 Ph.D. and MS students; several fellows and junior faculty.
- Bergan S, Brunet M, Hesselink DA, Johnson-Davis KL, Kunicki PK, Lemaitre F, Marquet P, Molinaro M, Noceti O, Pattanaik S, Pawinski T, Seger C, Shipkova M, Swen JJ, van Gelder T, Venkataramanan R, Wieland E, Woillard JB, Zwart TC, Barten MJ, Budde K, Dieterlen MT, Elens L, Haufroid V, Masuda S, Millan O, Mizuno T, Moes DJAR, Oellerich M, Picard N, Salzmann L, Tönshoff B, van Schaik RHN, Vethe NT, Vinks AA, Wallemacq P, Åsberg A, Langman LJ. Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Ther Drug Monit. 2021 Apr 1;43(2):150-200. doi: 10.1097/FTD.0000000000000871. PMID: 33711005.
- Caritis SN, Venkataramanan R. Obstetrical, fetal, and lactation pharmacology-a crisis that can no longer be ignored. Am J Obstet Gynecol. 2021 Jul;225(1):10-20. doi: 10.1016/j.ajog.2021.02.002. PMID: 34215351.
- Pilch NA, Sell ML, McGhee W, Venkataramanan R. Important considerations for drugs, nutritional, and herbal supplements in pediatric solid organ transplant recipients. Pediatr Transplant. 2021 Feb;25(1):e13881. doi: 10.1111/petr.13881. Epub 2020 Nov 3. PMID: 33142023.
- Chaphekar N, Dodeja P, Shaik IH, Caritis S, Venkataramanan R. Maternal-Fetal Pharmacology of Drugs: A Review of Current Status of the Application of Physiologically Based Pharmacokinetic Models. Front Pediatr. 2021 Nov 3;9:733823. doi: 10.3389/fped.2021.733823. PMID: 34805038; PMCID: PMC8596611.
- Dodeja P, Giannoutsos S, Caritis S, Venkataramanan R. Applications of Volumetric Absorptive Microsampling Technique: A Systematic Critical Review. Ther Drug Monit. 2023 Aug 1;45(4):431-462. doi: 10.1097/FTD.0000000000001083. Epub 2023 Mar 6. PMID: 36917733.
- Almazroo OA, Miah MK, Pillai VC, Shaik IH, Xu R, Dharmayan S, Johnson HJ, Ganesh S, Planinsic RM, Demetris AJ, Al-Khafaji A, Lopez R, Molinari M, Tevar AD, Hughes C, Humar A, Venkataramanan R. An evaluation of the safety and preliminary efficacy of peri- and post-operative treprostinil in preventing ischemia and reperfusion injury in adult orthotopic liver transplant recipients. Clin Transplant. 2021 Jun;35(6):e14298. doi: 10.1111/ctr.14298. Epub 2021 May 5. PMID: 33764591; PMCID: PMC8243925.
- Thanukrishnan H, Venkataramanan R, Mehta RB, Jorgensen D, Sood P. The combination of exposure to Tacrolimus, mycophenolic acid, Inosine 5'-Monophosphate Dehydrogenase activity and inhibition in the first week define early histological outcomes in renal transplant recipients. Clin Transplant. 2022 Dec;36(12):e14830. doi: 10.1111/ctr.14830. Epub 2022 Oct 26. PMID: 36177865.
- Hansen-Estruch C, Bikhet MH, Shaik IH, Vasudevan V, Zhao W, Javed M, Collins DE, Ayares D, Judd E, Cooper DKC, Venkataramanan R. Assessment of glomerular filtration and tubular secretion in baboons with life-supporting pig kidney grafts. Xenotransplantation. 2023 Mar;30(2):e12795. doi: 10.1111/xen.12795. Epub 2023 Feb 23. PMID: 36820525; PMCID: PMC10354795.
- Caritis SN, Costantine MM, Clark S, Stika CS, Kiley JW, Metz TD, Chauhan SP, Venkataramanan R; Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetric-Fetal Pharmacology Research Centers Network. Relationship between plasma concentration of 17-hydroxyprogesterone caproate and gestational age at preterm delivery. Am J Obstet Gynecol MFM. 2023 Jul;5(7):100980. doi: 10.1016/j.ajogmf.2023.100980. Epub 2023 Apr 24. PMID: 37100349; PMCID: PMC10330330.
- Almazroo OA, Shaik IH, Hughes CB, Humar A, Venkataramanan R. Treprostinil Supplementation Ameliorates Hepatic Ischemia Reperfusion Injury and Regulates Expression of Hepatic Drug Transporters: An Isolated Perfused Rat Liver (IPRL) Study. Pharm Res. 2022 Nov;39(11):2979-2990. doi: 10.1007/s11095-022-03384-x. Epub 2022 Sep 7. PMID: 36071353; PMCID: PMC9633539.
- Borda LA, Någård M, Boulton DW, Venkataramanan R, Coppola P. A systematic review of pregnancy-related clinical intervention of drug regimens due to pharmacokinetic reasons. Front Med (Lausanne). 2023 Nov 29;10:1241456. doi: 10.3389/fmed.2023.1241456. PMID: 38093976; PMCID: PMC10716708.
- Feturi FG, Zhang W, Erbas VE, Dong L, Sahin H, Zhang Z, Oksuz S, Spiess AM, Solari MG, Venkataramanan R, Gorantla VS. Topical Tacrolimus and Mycophenolic Acid Therapy Synergizes with Low Dose Systemic Immunosuppression to Sustain Vascularized Composite Allograft Survival. J Pharm Sci. 2024 Feb 1:S0022-3549(24)00020-0. doi: 10.1016/j.xphs.2024.01.015. Epub ahead of print. PMID: 38309457.