Eric Lagasse, PharmD, PhD

Associate Professor of Pathology, Division of Experimental Pathology

Dr. Lagasse is a member of the Division of Experimental Pathology and the McGowan Institute for Regenerative Medicine.

Education & Training
PharmD - 1985, Louis Pasteur University, Strasbourg, France
PhD - 1989, University of Basel, Switzerland
Research Interests

My research is focused primarily on stem cell biology and cell-based therapy for a variety of diseases including cancer. Specific areas of interest comprise cell-based therapy for liver disease, ectopic organogenesis, bioartificial tumors development and identification of normal and cancer stem cells.

Representative Publications

View Dr. Lagasse's publications on PubMed.

  • Manohar, R., Komori J., Guzik L., Stolz D. Chandran U.R. LaFramboise W.A. and Lagasse E. (2011). Identification and Expansion of a Unique Stem Cell Population from Adult Mouse Gallbladder. Hepatology. 54:1830-41.
  • Soto-Gutierrez A., Zhang L., Medberry C., Fukumitsu K., Faulk D., Jiang H., Reing J., Gramignoli R., Komori J., Ross M., Nagaya M., Lagasse E., Stolz D., Strom S.C., Fox I.J., and Badylak S. (2011) A Whole Organ Regenerative Medicine Approach for Liver Replacement. Tissue Engineering Part C. Jun;17(6):677-86. PMID: 21375407.
  • Hoppo, T., Komori, J. Manohar R., Stolz D.B. and Lagasse E. (2011). Rescue of Lethal hepatic failure by hepatized lymph nodes in mice. Gastroenterology. 140 (2) 656-666.
  • Chandler J. and Lagasse E. (2010). Cancerous Stem Cells: Deviant Stem Cells with Cancer Causing Misbehavior. Stem Cell Research & Therapy. 1 (2): 13.
  • Manohar R. and Lagasse E. (2009). Transdetermination: a new trend in cellular reprogramming. Molecular Therapy. 17 (6): 936-938.
  • Teisanu, R.M., Lagasse E., Whitesides J. and Stripp B. R. (2008). Prospective Isolation of Bronchiolar Stem Cells. Stem Cells. 27(3):612-22.
  • Odoux C., Fohrer F., Hoppo T., Guzik T., Stolz D.B., Lewis D.W., Gollin S.M., Gamblin T.C., Geller D.A., and Lagasse E. (2008). A Stochastic Model for Cancer Stem Cell Origin. Cancer Research. 68: 6932-41.
  • Lagasse E. (2008). Cancer Stem Cells with Genetic Instability: The Best Vehicle with the Best Engine for Cancer. Gene Therapy. 15:136-142.
  • Xiong A., Austin W.T., Lagasse E., Uchida N., Tamaki S., Bordier B., Weissman I.L. Glenn JS and Millan M. Isolation of Human Fetal Liver Progenitors and their Enhanced Proliferation by 3-Dimensional Co-culture with Endothelial Cells. Tissue Eng. (2008). Part A. Apr 23.
  • Rajasekhar V. K., Dalerba P., Passegué E., Lagasse E., Najbauer J. Meeting report. The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007. Stem Cells. (2008). 26:292-298.