Catherine K. Gestrich, DO

Assistant Professor of Pathology, Division of Pediatric Pathology

Dr. Gestrich is a member of the Division of Pediatric Pathology.

Clinical Expertise

Pediatric soft tissue tumors, molecular genetic pathology, vascular anomalies, pediatric brain tumors

Certifications

The American Board of Pathology – Anatomic & Clinical Pathology
The American Board of Pathology – Molecular Genetic Pathology

Education & Training
DO - West Virginia School of Osteopathic Medicine (2017)
Residency in Anatomic & Clinical Pathology - Case Western Reserve University (2021)
Pediatric Pathology Fellowship - Boston Children’s Hospital/Harvard Medical School (2022)
Molecular Genetic Pathology Fellowship - University of Pittsburgh Medical Center (2023)
Research Interests

Molecular aspects of pediatric solid tumors, including brain tumors

Representative Publications

Gestrich CK, De Lancy SJ, Kresak A, Meyerson H, Pateva I, Yalley AK, Ryder C, Shetty S, Bledsoe J, Moore EM, Oduro KA Jr. IGJ and SPATS2L immunohistochemistry sensitively and specifically identify BCR::ABL1+ and BCR::ABL1-like B-acute lymphoblastic leukaemia. Br J Haematol. 2023 Oct 23. doi: 10.1111/bjh.19142. PMID: 37871900.

Gestrich CK, Vivero MP, Konczyk DJ, Goss JA, Labow BI, Pearson GD, Cottrell CE, Mathew MT, Prasad V, Kozakewich HP, Fletcher CDM, Greene AK, Al-Ibraheemi A. Papillary Hemangioma Harbors Somatic GNA11 and GNAQ mutations. Am J Surg Pathol. 2023 Sep 26. doi: 10.1097/PAS.0000000000002127. PMID: 37750536.

Gestrich C, Davis JL, Biederman L, John I, Alaggio R, Giovannoni I, Arnold MA, Shenoy A, Tchakarov A, Al-Ibraheemi A. ALK-rearranged Epithelioid Mesenchymal Neoplasm: Expanding the Spectrum of Tyrosine Kinase Altered Mesenchymal Tumors. Mod Pathol. 2023 Sep 17:100334. doi: 10.1016/j.modpat.2023.100334. PMID: 37726067.

Gestrich CK, De Lancy SJ, Kresak A, Sinno MG, Yalley A, Pateva I, Meyerson H, Shetty S, Oduro KA Jr. Mucin 4 protein is expressed in B-acute lymphoblastic leukemia and is restricted to BCR::ABL1-positive and BCR::ABL-like subtypes. Hum Pathol. 2023 Jun;136:75-83. doi: 10.1016/j.humpath.2023.03.018. Epub 2023 Apr 5. PMID: 37023866.

Gestrich CK, Couce ME, Cohen ML. Adult Diffuse Astrocytic and Oligodendroglial Tumors. Neurosurgery. 2021 Oct 13;89(5):737-749. doi: 10.1093/neuros/nyab042. PMID: 33611566.

Crawford E, Gestrich C, Malay S, Young D, Perry S, Splawski J, Sferra TJ, Saab S, Moses J. Association of Fecal Calprotectin With Endoscopic and Histologic Activity in Pediatric Inflammatory Bowel Disease. JPGN Rep. 2021 Oct 13;2(4):e129. doi: 10.1097/PG9.0000000000000129. PMID: 37206450.

Gestrich CK, Jajosky AN, Elliott R, Stearns D, Sadri N, Cohen ML, Couce ME. Molecular Profiling of Pediatric and Adult Glioblastoma. Am J Clin Pathol. 2021 Mar 15;155(4):606-614. doi: 10.1093/ajcp/aqaa172. PMID: 33210143.