Bryan Rea, MD

Assistant Professor of Pathology, Division of Hematopathology

Dr. Rea is a member of the Division of Hematopathology.

Clinical Expertise

Hematopathology, Surgical Pathology

Education & Training
BS - Illinois Wesleyan University, 2009
MD - University of Illinois College of Medicine, 2013
Residency - Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, 2017
Fellowship - Surgical Pathology, Hospital of the University of Pennsylvania, Philadelphia, 2018
Fellowship - Hematopathology, UPMC, 2019
Research Interests

Cytogenetic and molecular genetic characterization of hematopoietic neoplasms.

Representative Publications
  • Rea B, Liu YC, Maguire A, Soma LA, Bacon CM, Bayerl MG, Smith MH, Barrett MT, Swerdlow SH, Gibson SE. Genomic landscape of Epstein-Barr virus-positive extra nodal marginal zone lymphomas of mucosa­associated lymphoid tissue. Mod Pathol. 2022 Jul;35(7):938-945.
  • Liu YC, Illar G, Al Amri R, Canady B, Rea B, Yatsenko S, Geyer J. Therapy-related myeloid neoplasms with different latencies: a detailed clinicopathologic analysis. Mod Pathol. 2022 May;35(5):625-631.
  • Al Amri R, Rea B. Anaplasmosis with associated haemophagocytic lymphohistiocytosis. Br J Haematol. 2021 Aug;194(4):657.
  • Rea B, Bailey NG. Additional characterization of LEF1 expression in nodular lymphocyte predominant Hodgkin lymphoma and classic Hodgkin lymphoma. Ann Diagn Pathol. 2021 March 15;52:151730.
  • Carlsen E, Bailey N, Aggarwal N, Wild M, Yatsenko SA, Rea B, Liu YC. Clinicopathologic Characterization of Hypocellular Acute Myeloid Leukemia Showed Fewer Genetic Abnormalities Involving Cell Proliferation and NPM1 When Compared to Non-Hypocellular Acute Myeloid Leukemia. Am J Clin Pathol. 2020 Oct 22;aqaa150.
  • Rea B, Bailey NG. Acute Myeloid Leukaemia With t(8;16)(p11.2;p13.3) and Erythrophagocytosis. Br J Haematol. 2020 Jul;190(2):133.
  • Rea B, Aggarwal N, Yatsenko SA, Bailey N, Liu YC. Acute myeloid leukemia with isolated del(5q) is associated with IDH1/IDH2 mutations and better prognosis when compared to acute myeloid leukemia with complex karyotype including del(5q). Mod Pathol. 2020 Apr;33(4):566-575.
  • Rea B, Peel RL, Han M, Ohori NP, Aggarwal N. lntravascular Large B-cell Lymphoma Involving Multinodular Goiter and Mimicking Carcinoma. Int J Surg Pathol. 2020 Aug;28(5):517-518.
  • McMahon CM, Canaani J, Rea B, Sargent RL, Qualtieri JN, Watt CD, Morrissette JJD, Carroll M,Perl AE. Gilteritinib induces differentiation in relapsed and refractory FLT3-mutated acute myeloid leukemia. Blood Adv. 2019 May 28;3(10):1581-1585.
  • Wang J, Rea B, Haun P, Emerson R, Kirsch I, Bagg A. High-Throughput Sequencing of the T-cell receptor beta chain gene distinguishes two subgroups of cutaneous T-cell lymphoma. J Am Acad Dermatol. 2019 Apr;80(4):1148-1150.e1.
  • Rea B, Haun P, Emerson R, Vigna Ii M, Farooqi M, Samimi S, Elenitsas R, Kirsch I, Bagg A. Role of high­throughput sequencing in the diagnosis of cutaneous T-cell lymphoma. J Clin Pathol. 2018 Sep;71(9):814-820.
  • Wang SA, Hasserjian RP, Tam W, Tsai AG, Geyer JT, George Tl, Foucar K, Rogers HJ, Hsi ED, Rea BA, Bagg A, Bueso-Ramos C, Arber DA, Verstovsek S, Orazi A. Bone marrow morphology is a strong discriminator between chronic eosinophilic leukemia, not otherwise specified from reactive idiopathic hypereosinophilic syndrome. Haematologica. 2017 Volume 102(8):1352-1360.
  • Rea B, Frank D. An uncommon manifestation of acute leukemia. Gastrointestinal Endoscopy. 2017 Jul;86(1):240-242. Epub 2016 Dec 22.
  • Wang SA, Tam W, Tsai A, Arber DA, Hasserjian RP, Geyer JT, George T, Czuchlewski DR, Foucar K, Rogers HJ, Hsi E, Rea B, Bagg A, Dal Cin P, Kelley T, Verstovsek S, Bueso-Ramos C, Orazi A. Targeted Next Generation Sequencing Identifies a Subset of Idiopathic Hypereosinophilic Syndrome with Features Similar to Chronic Eosinophilic Leukemia, Not Otherwise Specified. Modern Pathology. 2016 
    Aug;29(8):854-64.
  • Rea B, Samulski TD, Strauser H, Aikawa V, Luger S, Bagg A. Chronic lymphocytic leukemia with a t(8;14)(q24;q32): FISHing catches a (sheepish) red herring. American Journal of Hematology. 2015 Dec;90(12):1187-8.