Alesia Kaplan, MD

Associate Professor of Pathology, Division of Transfusion Medicine

Dr. Kaplan is an Assistant Medical Director of a large Centralized Transfusion Service (CTS), Clinical Services Vitalant-Pittsburgh that provides clinical transfusion support to the UPMC health system hospitals. Dr. Kaplan is committed to research and to teaching medical technologists, medical students, residents and fellows.

Clinical Expertise

Dr. Kaplan has general expertise in transfusion medicine with particular interest in Patient Blood Management. Dr. Kaplan is responsible for the HIV/HCV lookback program.

Education & Training
MD - Vitebsk State Medical University, Belarus, 2006
AP/CP Residency - University of Minnesota, 2014
BB/Transfusion Medicine Fellowship - University of Minnesota, 2015
Awards
2014 University of Minnesota, Pathology, Ernst Award for Research
2016 and 2018 Best CP Teacher of the Year Award, University of Pittsburgh
Research Interests

Dr. Kaplan's research interests include Pathogen Inactivation Technologies for blood products and Patient Blood management. Dr. Kaplan is currently a primary investigator on the study sponsored by Cerus corporation looking at transfusion of pathogen inactivated RBCs in cardiac surgery patients.  Dr. Kaplan is working on two cold stored platelet clinical trials: Department of defense (DOD) funded Chilled Platelet Study (CHIPS)) trial in adult and pediatric patients undergoing cardiothoracic surgery and department of defense (DOD) funded Cold Stored Platelets Early Intervention-Traumatic Brain Injury (TBI) trial (CriSP-TBI). Dr. Kaplan participated as a co-investigator in an NIH funded Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO).

Representative Publications
  • Seheult JN, Tysarczyk M, Kaplan A, Triulzi DJ, Yazer MH. Optimizing blood bank resources when implementing a low-titer group O+ whole blood program: an in silico study. Transfusion. 2020 Aug;60(8):1793-1803.
  • Smith JA, Seheult JN, Sevcik J, Kiss JE, Kaplan A. Process mapping of the urgent red cell exchange procedure for patients with severe complications of sickle cell disease at a centralized hemapheresis service. J Clin Apher. 2020 Sep;35(5):427-434.
  • Seheult JN, Stram MN, Sevcik J, Kaplan A, Kiss JE. Benchmarking the centralized urgent plasma exchange service for patients admitted with a diagnosis of suspected acquired thrombotic thrombocytopenic purpura at a large healthcare system. J Clin Apher. 2021 Jun 25. doi: 10.1002/jca.21916. Epub ahead of print.
  • Korley FK, Durkalski-Mauldin V, Yeatts SD, Schulman K, Davenport RD, Dumont LJ, El Kassar N, Foster LD, Hah JM, Jaiswal S, Kaplan A, Lowell E, McDyer JF, Quinn J, Triulzi DJ, Van Huysen C, Stevenson VLW, Yadav K, Jones CW, Kea B, Burnett A, Reynolds JC, Greineder CF, Haas NL, Beiser DG, Silbergleit R, Barsan W, Callaway CW; SIREN-C3PO Investigators. Early Convalescent Plasma for High-Risk Outpatients with Covid-19. N Engl J Med. 2021 Aug 18:NEJMoa2103784. doi: 10.1056/NEJMoa2103784. Epub ahead of print.
  • Bubar R, Kiss JE, Triulzi DJ, D'Andrea P, Zilich A, Kaplan A. How do we…consistently provide high-dose granulocyte products for transfusions in neutropenic patients? Transfusion. 2023 Jul;63(7):1267-1276.
  • Thant M, Cancelas J, Kaplan A. The enhanced direct antiglobulin test in current practice has a limited impact on management of adult patients. Transfus Apher Sci. 2023 Aug 17:103768.