Congratulations to Assistant Professor of Pathology Hun-Way Hwang, MD, PhD of the Division of Experimental Pathology on the upcoming publication of his article, "A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway" in eLife Sciences Publications! This study presents a valuable finding on how mTORC signaling can impact metabolism by modulating the function of the APA machinery. The evidence supporting the claims of the authors is solid, with compelling data supporting the identification of a 'twin UGUA' motif that governs PAS selection by the CFIm complex, which is further connected to mTORC signaling. This work will have a general interest to those studying APA and cellular metabolism.