Research Interests
Pediatric Brain Tumor Immunotherapy; theranostics; immunoPET; Biomarkers; Adoptive cellular therapy; peptide vaccine immunotherapy.
Selected Publications
- Müller S, Agnihotri S, Shoger KE, Myers MI, Smith N, Chaparala S, Villanueva CR, Chattopadhyay A, Lee AV, Butterfield LH, Diaz A, Okada H, Pollack IF, Kohanbash G. Peptide vaccine immunotherapy biomarkers and response patterns in pediatric gliomas. JCI Insight 5;3(7), 2018.
- Chheda Z, Kohanbash G, Okada K, Jahan N, Sidney J, Pecoraro M, Carrera D, Shrivastav S, Liu S, Lin Y, Downey K, Chuntova P, Watchmaker P, Mueller S, Pollack I, Rajalingam R, Carcasboso A, Mann M, Sette A, Hou Y, Okada H. Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy. J Exp Med215(1):141-157, 2018.
- Kohanbash G, Carrera DA, Shrivastav S, Ahn BJ, Jahan N, Mazor Tali, Chheda ZS, Downey Kira M, Watchmaker PB, Beppler C, Warta R, Amankulor NA, Herold-Mende C, Costello JF, Okada H. IDH mutations suppress STAT1 and CD8+ T-cell accumulation in gliomas. J Clin Invest 127(4):1425-1437, 2017.
- Müller S, Kohanbash G, Liu JS, Alvarado B, Carrera D, Bhaduri A, Watchmaker P, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim D, Aghi MK, Okada H, Diaz A. Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment. Genome Biol 18(1):234, 2017.