This is a welcome message to all of you who visit the website of our department. This website is intended to provide a clear picture of our department's organization, capabilities, and commitment to excellence. Our department provides diagnostic support to the University of Pittsburgh Medical Center (UPMC) and training support to residents, clinical fellows, graduate students and postdoctoral trainees. In addition, it supports training of students in Pathology at the University of Pittsburgh School of Medicine, providing the standard and cutting-edge knowledge that the students will be required it to know for the practice of modern medicine in the 21st Century. The faculty of our department, who are united in this complex mission, share the fundamental belief that delivery of services and teaching are best provided on a platform supported by research. Such research covers basic mechanisms of tissue biology, inflammatory pathways associated with chronic disease, genomics and genetics of cancer, tissue committed stem cells and biology of transplantation and biocomputation in Pathology diagnostics. The multiple research laboratories of our department bring together different faculty groups and link academic activities within thematic topics. As a discipline, Pathology is sitting at crossroads. The accumulated discoveries from all aspects of basic science are rapidly translated into diagnostic endpoints. As personalized medicine identifies targets that differentiate disease responses, it is the task of pathology to translate these targets into useful practices and provide guidance to clinical groups, so that treatments become optimized based on evidence. To the extent that personalized medicine will be the practice of the 21st Century, and to the extent that personalized medicine is evidence-based medicine, pathology is the larger part of the evidence.
George K. Michalopoulos, MD, PhD
Maud Menten Professor and Chair
Department of Pathology
University of Pittsburgh School of Medicine and UPMC